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Longevity Stack

Measure your baseline. Optimize healthspan. Retest annually.

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CreusLife Editorial Team
Evidence reviewed · Peer-reviewed sources cited · Updated regularly
Last updated: May 2026 · Affiliate & editorial disclosure
ℹ️ Informational only — not medical advice. Some links are affiliate links at no extra cost to you. Full disclosure.
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Healthspan focusWant to stay capable, energetic, and sharp as long as possible
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Data-drivenAlready tracking some metrics — want a comprehensive baseline
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Labs curiousHeard about ApoB, hsCRP, insulin — want the full picture
Prevention focusFamily history of cardiovascular or cognitive decline
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Active adults 40+Train regularly but want an intelligent measurement layer
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Women 38+Hormonal transition amplifies every longevity marker
📋 Strong Longer Protocol

Muscle preservation is the most evidence-backed longevity intervention available. The Strong Longer Protocol is the longevity stack's active foundation.

Read the full protocol →
◉ Foundation — Start here
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Supplement — Core
Omega-3 — 2–4g EPA+DHA/day
Cardiovascular protection, cognitive support, anti-inflammatory. Among the most evidence-backed supplements for longevity-adjacent outcomes.
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Supplement — Core
Vitamin D3+K2 — 2,000–5,000 IU/day
Test first. Critical for bone density, immune function, and hormonal health. K2 directs calcium to bone.
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Supplement — Core
Magnesium glycinate — 400mg/night
Involved in 300+ enzymatic reactions. ~70% of US adults are deficient.
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Supplement — Core
Creatine monohydrate — 5g/day
Muscle, cognitive function, bone density, metabolic health. Safe for life. No loading required.
◉ Optimize — Add after 30 days
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Supplement
Urolithin A (Mitopure) — 500mg/day
Activates mitophagy. 15+ years of clinical research. Strongest evidence in adults 45+.
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Supplement
BodyHealth PerfectAmino
Complete essential amino acid support for muscle preservation and cellular function.
Wearable
Oura Ring — HRV + sleep staging
Daily biological age signal. HRV trending upward over months is one of the best signs your longevity protocol is working.
◉ Precision — Data-driven layer
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Labs
Function Health — 100+ biomarker panel
The most comprehensive annual baseline available. Covers heart, hormones, thyroid, nutrients, and inflammation in one draw.
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Labs
InsideTracker — biological age scoring
Tracks your InnerAge score — calculated biological age from biomarker data. Best for ongoing tracking.
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Labs
Quest Health — individual marker testing
Order specific markers between annual panels.
30
Days
• Confirm foundational supplements consistent
• Check vitamin D if not tested yet
• Establish wearable HRV baseline
90
Days
• Add Urolithin A if 45+
• Run VO2 max estimate on wearable
• Review sleep data trend
365
Days
• Full bloodwork panel — compare to baseline
• DEXA if available
• VO2 max recheck — target +3–5%
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Free resource
The CreusLife Health Baseline Blueprint

The exact labs, wearables, and metrics to establish your health baseline — organized by cardiometabolic, recovery, body composition, performance, and longevity.

No spam. Unsubscribe any time. Disclosure.

Not sure where this fits in your plan?

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Next Step
Start with your comprehensive baseline

A longevity stack without measurement is guesswork. Get ApoB, fasting insulin, hsCRP, and vitamin D before spending on supplements.

Genetics + labs

Add genetic risk context to your longevity stack

A longevity stack should not be built from averages alone. SelfDecode can help identify DNA-informed risk patterns across heart health, inflammation, metabolism, sleep, nutrition, and longevity so your stack is more targeted.

Explore SelfDecode
Supplementation after measurement

Preferred supplement partner: Momentous

Supplements should come after the baseline: labs, sleep, training, nutrition, and symptoms. For the supplements CreusLife recommends most often, Momentous is now the preferred partner because it offers focused products for performance, sleep, recovery, and longevity.

Start with the Momentous main store if you want to choose from the full lineup.

Build capacity

Longevity-supporting tools

The best longevity tools are the ones that help you build or preserve capacity: strength, heat tolerance, cold tolerance, and recovery.

Measure at home

Recommended home measurement tools

These tools are useful when you want to turn a protocol into a feedback loop instead of guessing.

Ready to build your health system?

Take the Stack Analyzer — 6 questions to a personalized measurement path, protocol, and supplement stack.