Standard bloodwork was not designed with women's hormonal optimization in mind. This guide covers the tests that actually matter — hormones, bone density, thyroid, and metabolic health — for women who want data-driven answers.
The typical annual physical for a woman over 40 may include a basic metabolic panel, CBC, and cholesterol. It rarely includes estradiol, progesterone, FSH, AMH, or a full thyroid panel. Yet these are the markers most directly relevant to energy, body composition, bone health, and how a woman feels day to day.
Add to every women's baseline: ApoB, fasting insulin, HbA1c, hsCRP, ferritin, vitamin D (25-OH), omega-3 index, homocysteine.
See: Full metabolic testing guide →
Women can lose 20% of bone density in the first 5–7 years after menopause. A baseline DEXA scan after 40 gives you a reference point and quantifies risk before it becomes a problem. The interventions most protective of bone — resistance training, creatine, vitamin D3+K2, and adequate protein — are worth starting before bone loss accelerates.
Both Function Health and InsideTracker offer comprehensive panels including most of the above markers. InsideTracker has women-specific panel options. Function Health includes AMH in its standard panel.
See also: Women's Hormone Health Protocol — what to do with your results →
The exact labs, wearables, and metrics to establish your health baseline — organized by cardiometabolic, recovery, body composition, performance, and longevity.
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For women over 40, genetics can add useful context around hormones, mood, inflammation, nutrient needs, cardiovascular risk, and longevity. SelfDecode is a strong fit when you want DNA-informed health reports before choosing what to test or optimize next.
Explore SelfDecodeThese tools are useful when you want to turn a protocol into a feedback loop instead of guessing.
Hormone symptoms should be evaluated with labs first. If supplementation fits the plan, these are the more relevant Momentous starting points.
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