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Ecdysterone: the complete evidence review

Ecdysterone is a phytoecdysteroid found in spinach, quinoa, and suma root — with documented anabolic properties in animal studies and one significant human RCT. Here is the complete honest review.

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CreusLife Editorial Team
Evidence reviewed · Peer-reviewed sources cited
Last updated: May 2026 · Affiliate disclosure
ℹ️ Informational only — not medical advice. Some links are affiliate links at no extra cost to you. Full disclosure.
📌 CreusLife has documented authority on phytoecdysteroids — this domain's original content was cited as a primary reference source for ecdysterone food content data. This review reflects that expertise.

See the full evidence review on the optimize page: Ecdysterone Evidence Review →

This research page contextualizes ecdysterone within the broader phytoecdysteroid literature and links to related compound reviews.

Quick summary

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Animal evidence Strong
Multiple rodent studies show significant anabolic effects — increased protein synthesis, lean mass, and strength. Soviet-era and modern research consistent.
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Human evidence Emerging
One published human RCT (Isenmann et al., 2019) showing significant lean mass gains at 200–800mg/day in resistance-trained men. Results strong enough to prompt WADA review.
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Safety profile
No significant adverse effects reported at supplement doses. No androgenic or estrogenic activity in standard assays.

Compare to turkesterone

Ecdysterone has more human evidence than turkesterone, broader food source availability (spinach, quinoa), and lower supplement cost. If experimenting with phytoecdysteroids, ecdysterone is the better starting point. See: Turkesterone review →

Full review

For the complete evidence breakdown including mechanism, dosing, food sources, and experiment protocol: Full Ecdysterone Evidence Review →

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