Function Health, InsideTracker, SiPhox, Quest Health, and Superpower compared on biomarker coverage, pricing, and who each platform is actually for. Not reviews — a decision matrix built around your goal and budget.
| Platform | Annual cost | Biomarkers | Draw method | ApoB | Lp(a) | Fasting insulin | Hormones | Best for |
|---|---|---|---|---|---|---|---|---|
| Function Health | $499/yr | 160+ | Quest lab | ✓ | ✓ | ✓ | ✓ | Comprehensive baseline, best value per biomarker |
| InsideTracker Ultimate | $489–$589 + $149/yr platform | 43–54 | Quest lab | ✓ | ✗ | ✓ | ✓ | Deep recommendations, biological age (InnerAge), DNA add-on |
| SiPhox Health | ~$95/quarter ($124/test) | 18–60+ | At-home finger prick | ✓ | ✗ (basic panels) | ✓ | ✓ (upper tiers) | Budget-first, at-home convenience, quarterly testing |
| Quest Health | Pay per test | Targeted (varies) | Quest lab | ✓ | ✓ | ✓ | ✓ | Targeted panels, no annual commitment, best for specific retesting |
| Superpower | ~$16–50/mo | 50+ | Lab draw | ✓ | Check current panel | ✓ | ✓ | Frequent retesting, subscription model with unlimited draws |
Prices as of May 2026. Function Health pricing has shown fluctuation between $365–$499 across different pages — verify at functionhealth.com before purchase. All platforms are HSA/FSA eligible. InsideTracker: NY, NJ, RI restrictions may apply.
→ Function Health at $499/year. 160+ biomarkers including ApoB, Lp(a), fasting insulin, full hormone panels, thyroid, liver, kidney, heavy metals, and more. Best per-biomarker value of any platform. Uses Quest labs nationwide. AI interpretation included.
→ InsideTracker Ultimate. Its recommendation engine links specific foods, exercises, and supplements to individual biomarker improvement — more structured than Function Health's interpretation layer. The InnerAge biological age score tracks whether interventions are actually working. 43–54 biomarkers at $489–$589/draw + $149/year platform. DNA analysis is a meaningful add-on at $249.
→ SiPhox Health. At-home finger-prick testing from $124/test or ~$95/quarter on a plan. Core panel covers metabolic, cardiovascular, inflammation, and key nutrients. Ultimate 360 adds hormones and advanced markers (60+ biomarkers). Results in 3–5 days. Not available in NY, NJ, RI. Good entry point before committing to Function Health's annual membership.
→ Quest Health direct-to-consumer. Order exactly the tests you need. No annual membership. 2,000+ locations. Results in 3–5 days. Best for targeted retesting (e.g., retest ApoB at 90 days after an intervention) without paying for a full annual panel.
→ Superpower (~$16–50/month, unlimited draws depending on tier). Subscription model with 50+ biomarkers. Good for people actively managing elevated markers (insulin resistance, ApoB, inflammation) who want to retest every 60–90 days without additional per-test costs.
Function Health is the best value for a comprehensive annual baseline. At $499/year (verify current pricing — the site has shown $365 in some contexts), it covers over 160 biomarkers across every major health category: metabolic (glucose, HbA1c, fasting insulin), cardiovascular (ApoB, Lp(a), full lipid panel, homocysteine), liver, kidney, thyroid (full panel including free T3, T4), sex hormones (testosterone, estradiol, SHBG, DHEA-S), immunity, nutrients (vitamin D, B12, ferritin, magnesium), and more.
The Lp(a) inclusion is particularly meaningful. The 2026 ACC/AHA guideline now recommends universal Lp(a) testing for all adults — a test absent from standard physicals that would cost $30–50 to order separately. Function includes it as part of the baseline at no extra cost.
Limitations: Function Health uses Quest labs for draws, so a lab visit is required. Interpretation is AI-driven and generally useful, but the recommendation depth is less structured than InsideTracker's. Function Health pricing has shown inconsistency between $365 and $499 across different pages and time periods — always verify current pricing before purchase and date-stamp your comparison screenshots.
InsideTracker's core differentiator is recommendation specificity. After your blood draw (43–54 biomarkers on Ultimate), InsideTracker links each out-of-range result to specific interventions: which foods raise HDL, which exercises lower cortisol, which supplements address vitamin D deficiency. The recommendation engine is more structured than Function Health's AI interpretation.
The InnerAge biological age score is genuinely useful for motivation and tracking. It gives you a single number that responds to interventions — if your InnerAge drops from 47 to 44 over 6 months, that's a concrete signal that your protocol is working at a systemic level.
Limitations: fewer biomarkers than Function Health at higher cost per biomarker. No Lp(a) in standard panels. DNA testing is a meaningful add-on but adds another $249. Better for depth of guidance than breadth of data.
| Key marker | Why it matters | Function | InsideTracker | SiPhox (Ultimate) | Quest |
|---|---|---|---|---|---|
| Fasting insulin | Earliest metabolic warning — not in standard panels | ✓ | ✓ | ✓ | ✓ |
| ApoB | Best cardiovascular particle risk marker | ✓ | ✓ | ✓ | ✓ |
| Lp(a) | 2026 ACC/AHA: universal testing recommended | ✓ | ✗ | ✗ (basic) | ✓ |
| hs-CRP | Systemic inflammation | ✓ | ✓ | ✓ | ✓ |
| Full thyroid panel | TSH + free T3 + free T4 | ✓ | ✓ | ✓ | ✓ |
| Testosterone + SHBG | Free hormone availability | ✓ | ✓ | ✓ (Ultimate) | ✓ |
| Homocysteine | Cardiovascular + cognitive risk | ✓ | Check current panel | Check current panel | ✓ |
| Ferritin | Iron storage — common deficiency in women | ✓ | ✓ | ✓ | ✓ |
| Biological age score | Tracks whether interventions are working systemically | ✗ | ✓ InnerAge | ✗ | ✗ |
Panel contents subject to change. Verify current biomarker inclusion directly with each platform before purchase. Panels shown reflect offerings as of May 2026.
Order fasting insulin, ApoB, Lp(a), and vitamin D in one draw — no doctor required. Results in 3–5 days.